DRUGS FOR SEIZURES

Cards (162)

  • Nerve Impulse Nerve cell fiber resting potential
    ▪ Na+ concentration higher on _____
    ▪ K+ concentration higher on _____
    outside; inside
  • Nerve Impulse Nerve cell fiber resting potential
    ▪ Negative charge on ____
    ▪ Positive charge on _____
    inside; outside
    • Na+ rush inside cell
    Depolarization
  • K+ rush out to restore balance
    Repolarization
  • Repolarization moves in one direction
    Depolarization
  • Excessive abnormal electrical discharge from cortical neurons Causes: idiopathic, CNS infection, fever, metabolic disturbance , cerebral trauma, physical findings or changes in behavior that occur after an episode of abnormal electrical activity in the brain

    Seizures
  • term "_____" is often used interchangeably with "convulsion.“
    seizure
  • occur when a person's body shakes rapidly and uncontrollably. violent, involuntary contractions of the voluntary muscles.
    Convulsions
  • recurrent unprovoked seizure
    Epilepsy
  • Phases of seizure
    – may precede the seizure by hours or days.

    prodome
  • Phases of seizure
    — the seizure itself. In some cases, a scream or cry heralds its onset.
    ICTAL PHASE
  • Phases of seizure
    – takes place immediately after the seizure
    POSTICTAL PHASE
  • in behavior or mood typically occurs during the prodrome. This phase may include an aura – subjective sensation, such as unusual smell or flashing light
    PRODROME
  • The patient typically exhibits lethargy, confusion, and behavioral changes
    Postictal
  • a chronic seizure disorder, or group of disorders, characterized by seizures that usually recur unpredictably in the absence of a consistent provoking
    EPILEPSY
  • factor. derived from the Greek word meaning “to seize upon” or “taking hold of.” first described by Hughlings Jackson as an intermittent derangement of the nervous system due to a sudden, excessive, disorderly discharge of cerebral neurons.
    EPILEPSY
  • to throw or toss with a quick abrupt motion.
    Jerking
  • an abnormal sensation, typically tingling or pricking

    Paresthesia
  • language disorder marked by deficiency in the generation of speech
    Dysphasia
  • rare movements when the present feels like the past.
    Deja vu
  • most common seizure type occurring in approximately 80% of epileptic patients. clinical and EEG changes indicate initial activation of a system of neurons limited to part of one cerebral hemisphere that may spread to other or all brain areas
    Partial seizures
  • CLASSIFICATION OF PARTIAL SEIZURES
    ▪ generally do not cause loss of consciousness
    SIMPLE PARTIAL SEIZURES
  • SIMPLE PARTIAL SEIZURES
    SIGNS AND SYMPTOMS:
    MOTOR SIGNS: 

    convulsive jerking, chewing motions and lip smacking
  • SIMPLE PARTIAL SEIZURES
    SIGNS AND SYMPTOMS:
    SENSORY AND SOMATOSENSORY MANIFESTATIONS:
    paresthesias and auras
  • SIMPLE PARTIAL SEIZURES
    SIGNS AND SYMPTOMS:
    AUTONOMIC SIGNS:

    sweating, flushing and pupil dilation.
  • SIMPLE PARTIAL SEIZURES BEHAVIORAL MANIFESTATIONS:
    sometimes accompanied by impaired consciousness, include
    déjà vu expériences,
    structured hallucinations,
    ▪ and dysphasia
  • CLASSIFICATION OF PARTIAL SEIZURES
    ▪ accompanied by impaired consciousness; however in some cases, the impairment precedes or follows the seizures
    COMPLEX PARTIAL SEIZURES
  • MANIFESTATIONS
    ▪ Purposeless behavior is common.
    ▪ The affected person may have a glassy stare, may wander about aimlessly, and may speak unintelligibly.
    Psychomotor (temporal lobe) epilepsy may lead to aggressive behavior (e.g., outbursts of rage or violence).

    COMPLEX PARTIAL SEIZURES
  • COMPLEX PARTIAL SEIZURES
    • ______— usually persists for 1-2 minutes after the seizure ends.
    Postictal confusion
  • COMPLEX PARTIAL SEIZURES
    • ______ (e.g., picking at clothes) — common and may follow visual, auditory or olfactory hallucinations).
    Automatism
  • Entire brain is involved,motor manifestations are bilateral. diffuse, affecting both cerebral hemispheres. clinical and EEG changes indicate initial involvement of both hemispheres.
    GENERALIZED SEIZURES
  • GENERALIZED SEIZURES:
    ABSENCE (Petit mal) SEIZURES
    MYOCLONIC SEIZURES (bilateral massive epileptic myoclonus)
    CLONIC SEIZURES
    TONIC SEIZURES
    GENERALIZED-TONIC-CLONIC
    SEIZURES (grand mal)
    ATONIC SEIZURES (drop attacks)
  • present as alterations of consciousness (absences) lasting 10-30 seconds. Staring (with occasional eye blinking) and loss or reduction in postural tone is typical. Enuresis

    ABSENCE (Petit mal) SEIZURES
  • present as involuntary jerking of the facial, limb, or trunk muscles, possibly in rhythmic manner.

    MYOCLONIC SEIZURES (bilateral massive epileptic myoclonus)
  • MYOCLONIC SEIZURES aka
    bilateral massive epileptic myoclonus
  • ▪ consist of sporadic jerks, usually on both sides of the body. Patients sometimes describe the jerks as brief electrical shocks. When violent, these seizures may result in dropping or involuntarily throwing objects.
    MYOCLONIC SEIZURES
    • characterized by sustained muscle contractions alternating with relaxation
    CLONIC SEIZURES
    • are repetitive, rhythmic jerks that involve both sides of the body at the same time.

    CLONIC SEIZURES
    • involve sustained tonic muscle extension (stiffening).
    TONIC SEIZURES
  • ▪ cause sudden loss of consciousness
    GENERALIZED-TONIC-CLONIC SEIZURES (grand mal)