Hypogonadism

• Types of testicular infertility (hypogonadism)

  Pre-testicular infertility

  Testicular infertility

  Post-testicular infertility
• Pre-testicular infertility

  • Secondary hypogonadism
  • Due to hypothalamic / pituitary lesions
  • Testosterone, LH & FSH
  • Normal/Decreased
• Testicular Infertility

  • Primary hypogonadism
  • May be congenital / acquired
  • Congenital
  • Cryptorchism
  • Klinefelter’s syndrome
  • 5-alpha reductase def
  • Testosterone to Dihydrotestosterone (most potent form)
  • Acquired
  • Varicocele
  • Tumor
  • Orchitis

  Dec Testosterone, Inc FSH, LH
• Post testicular infertility

  • Due to disorders of sperm transport and function
  • Testosterone, FSH, LH- Normal