system of blood vessels with a pump and valves to ensure one-way flow of blood
Single circulation (of a fish):
fish has two chambers, one atrium & and one ventricle
it sends blood to the gills, where it is oxygenated
the blood then flows to all parts of the body before returning to the heart
known as single circulation because the blood goes through the heart once for each complete circulation of the body
pressure is lost as the blood passes through the capillaries of the gills and is not built back up again until the blood returns to the heart
this makes single circulation inefficient
Pulmonary circuit -
reference to the lungs
circulation between heart and lungs
collects oxygenated blood from the lungs and pumps it to the body
Systemic circuit:
circulation between heart and whole body
the right side of the heart collects deoxygenated blood from the body and pumps it to the lungs
pressure needs to be high in order to be able to transport the blood throughout the entire body
Advantages of double circulation:
lungs and heart are close together, so the pressure of the blood in the pulmonary circuit must be sent slower (in comparison to the systemic circuit) if it was faster, the blood veins would rupture
efficient as there’s separate pressures, high pressure for the systemic circuit, low pressure for the pulmonary circuit
Comparison of two circulations:
A) 1
B) low
C) fish
D) absent
E) 2
F) 2
G) high
H) reptiles
I) amphibians
J) birds
K) mammals
L) present
M) 4
ventricle:
thickness of wall on the left> thickness of wall on the right
needs to build up enough pressure to pump the blood to all of the main organs
the right ventricle pumps blood only to the lungs, which is a shorter distance
atria:
thickness of atria walls<thickness of ventricle walls
because the contraction of the atria only needs to be powerful enough to move blood down into the ventricles, while the ventricles are moving blood around the body and through all of the organs
septum divides the left side of the heart from the right side
prevents the mixing of oxygenated and deoxygenated blood
Flow of blood:
right atrium (via vena cava)
right ventricle (through atrioventricular valve)
pulmonary artery (through semilunar valve)
left atrium (via pulmonary vein)
left ventricle (through atrioventricular valve)
aorta (all around body)
Blood flow -
deoxygenated blood → right atrium via vena cava
heart gives a beat & blood is pushed through atrioventricular valve → right ventricle
walls of the ventricle contract, blood → pulmonary artery through semilunar valve
blood → lungs, moves through capillaries
has to be low pressure for this – capillaries which would burst under higher pressure
oxygenated blood → left atrium via pulmonary vein
passes through atrioventricular valve into the left ventricle
walls of the ventricle contract to push the blood into aorta and all the way around the body
Effect of physical activity on heart rate:
heart rate increases from the resting rate and stays high until physical activity slows down or stop
heart rate increases to supply the muscles with more oxygen and glucose a
needed to allow the muscles to respire aerobically, so they have sufficient energy to contract
after exercise, the heart rate gradually returns to normal
Coronary artery disease:
coronary artery is the artery that transfers blood to the heart
coronary heart disease is caused by blockage of the coronary arteries, which supply the heart with oxygen and glucose
people get heart attack from lack of oxygen to part of heart
How CHD forms:
fat deposits form plaque
fat starts to narrow down the lumen
the blood that can go through becomes limited
eventually - causes a difference in pressure that causes the layer, plaque and wall to rupture
blood clot + fat blocks off the blood vessel
RISK OF CHD: Poor diet with too much saturated (animal fat)
Leads to fatty deposits (atheroma) in arteries, which eventually block the blood vessel or allow a blood clot to form
RISK OF CHD: Obesity
Being overweight puts extra strain on the heart and makes it more difficult for the person to exercise
RISK OF CHD: Smoking
Nicotine damages the heart and blood vessels
RISK OF CHD: Stress
Tends to increase blood pressure, which can result in fatty materials collecting in the arteries
RISK OF CHD: Lack of exercise
The heart muscle loses its tone and becomes less efficient in pumping blood
RISK OF CHD: Genetic predisposition
Heart disease appears to be passed from one generation to the next in some families
RISK OF CHD: Age
Risk increases with age
RISK OF CHD: Sex
Males are more at risk than females
Treatment for Coronary heart disease -
Stent:
is used to expand the blood vessel and allow good flow of blood
Bypass surgery:
an alternate route is provided for blood to flow
three blood vessels:
artery
vein
capillary
Artery:
Thick, tough wall with muscles, elastic fibres and fibrous tissue
Carries blood at high pressure – prevents bursting and maintains pressure wave
Lumen quite narrow, but increases as a pulse of blood passes through
This helps to maintain blood pressure
Valves absent
The high pressure prevents blood flowing backwards, so valves are not necessary
Vein:
The walls are mainly fibrous tissue, with little muscle and few elastic fibres
Carries blood at low pressure
Lumen large
This reduces resistance to blood flow
Valves present
To prevent backflow of blood
Capillary
Permeable wall, one cell thick, with no muscle or elastic tissue
Allows diffusion of materials between capillary and surrounding tissues
White blood cells can squeeze between cells of the wall
Lumen approximately one red blood cell wide
Red blood cells pass through slowly to allow diffusion of materials and tissue fluid
Valves absent
Blood is still under pressure
Heart:
A) pulmonary artery
B) vena cava
C) right atrium
D) semilunar valve
E) atrioventicular valve
F) right ventricle
G) muscular wall
H) aorta
I) pulmonary vein
J) left atrium
K) semilunar valve
L) atrioventicular valve
M) tendon
N) left ventricle
O) septum
Kidney:
A) vena cava
B) renal vein
C) right kidney
D) aorta
E) renal artery
F) left kidney
Functions:
red blood cells = transporting oxygen
white blood cells = phagocytosis and antibody reproduction
platelets = clotting
plasma = transport of blood cells, ions, nutrients, urea, hormones & carbon dioxide
Lymphocytes -
are involved in the production of antibodies, which are needed to fight disease
antibodies can attach themselves to antigens (foreign proteins) and clump them together
Phagocytes -
have the ability to change their shape
move to engulf pathogens by a process called phagocytosis
Blood Clotting:
platelets are essential for blood clotting
blood thinners oppose this and stop clotting from happening (people who take blood thinners usually have stents in their hearts) (blood thinners is also a type of medicine)
prevents blood loss
prevents entry of pathogens
Process of blood clotting -
platelets clump together when tissues are damaged and block the smaller capillaries
platelets and damaged cells at the wound produce a substance that acts on a soluble plasma protein called fibrinogen
fibrinogen is changed into insoluble fibrin, which forms a network of fibres across the wound
red blood cells become trapped in this network and so form a blood clot