1. Collect a small sample of blood, generally a full 1 ml³
2. Blood can be drawn via an arterial stick from the wrist, groin, or above the elbow
3. The radial artery on the wrist is most commonly used to obtain the sample
4. The femoral artery and brachial artery can be used if necessary
5. If the patient already has a pre-existing arterial line, this can be used to obtain the sample
6. Once the blood is obtained, it is either sent to the hospital's central lab for analysis or tested by the respiratory therapist on the unit's blood gas analyzer