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HISTOLOGY MIDTERMS
Immune system and Lymphoid organs
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Cards (69)
First line of defense of an intruding pathogen?
Innate immunity
An antigen-indpendent?
Innate immunity
specific?
Adaptive immunity
non-specific?
innate immunity
An antigen-dependent?
Adaptive immunity
Used by the host immediately or within hours of encountering an antigen?
Innate immunity
Develops more slowly and is based on antigen presentation to lymphocytes?
Adaptive
immunity
Acquired gradually by exposure to microorganism?
Adaptive immunity
Include physical barriers such as the skin and mucuous membranes?
Innate immunity
Innate immunity proteins:
Hydrochloric acid
Defensins
Lysozyme
Complement
Interferons
Involves leukocytes and proteins?
Innate immunity
Short cationic polypetides?
Defensins
Hydrolyzes bacterial cell wall components?
Lysozymes
Kill bacteria by distrupting cell wall?
Defensins
A system of proteins in blood plasma, mucus and macrophages?
Complement
React with bacterial surface components to aid for removal of bacteria?
Complement
Paracrine factors from leukocytes and virus infected cells that signals NK cells?
Interferons
Response in B and T lymphocytes?
Adaptive immunity
Recognized by lymphocytes to elicit specific immune response against them?
Antigen
Immunoglobulins produced by plasma cells after a progenitor B cell is activated by specific antigen?
Antibodies
Cell surface glycoproteins whose primary function is to present peptide fragments for recognition T cells lymphocyte?
Major Histocompatibility Complexes
Founds on surfaces of all nucleated cells bear fragments of their constituents protein?
MHC Class I Molecules
Only antigen-presenting cells?
MHC Class II Molecules
Antibodies are primarily responsible for the response?
Humoral immunity
B cell lymphocyte is a principally responsible for this method?
Humoral immunity
Mature T lymphocyte, macrophages and cytokines are the main drivers here?
Cell-mediated immunity
The stem cell for all lymphocyte are located in?
Red Bone Marrow
Where is the Maturation of lymphoid organ occurs?
Primary
Where is the activation of lymphoid organs and became functional?
Secondary
Primary Lymphoid organs
Bone Marrow
for
B lymphocyte
Thymus
for
T lymphocyte
Secondary Lymphoid organs
Lymph nodes
MALT
Spleen
Bilobed organ in the mediastinum?
Thymud
Most active and prominent before puberty and undergoes involution with less activity on adult?
Thymus
Primary organ where T cell is produced?
Thymus
Originates from
endoderm
?
Thymus
Darkyl basophilic?
Thymic cortex
Contains extensive population of T lymphoblast?
Thymic cortex
Parts of thymic cortex
Squamous cells
Stellate epithelial cells
Squamous cortical cells
Parts of Thymic medulla
Cytoreticulum
Secondary layer
Hasaal corpuscles
Blood-thymus barrier that is responsible in preventing unregulated exposure of thymocyte to the antigens?
Squamous cells
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