Used to manage balance through the tonicity of the solution
IV solutions that contain electrolytes and other agents that mimic the body's ECF are used to replace depleted fluid and promote urine output
Crystalloid drug examples
5% dextrose & water
Normal saline
Lactated ringers
5% dextrose and ½ normal saline
Crystalloids
Water with electrolytes that form a solution that can pass through semipermeable membrane
Colloids
Substances such as large protein molecules that do not readily dissolve into true solutions
Colloids
Expands volume= albumin is key example
Expands the ECF volume through replacement of proteins, starches, or other large molecules
Colloid drug examples
Serum albumin
Dextran 40
Blood products
Plasma
Cryoprecipitate
RBC
WBC
Platelets
Tonicity
Describes the osmolarity of a solution relative to plasma
Isotonic
A solution that has the same osmolality as bodily fluids
Isotonic solutions do not result in any movement across the membrane through osmosis or diffusion
Isotonic solutions
Indicated for patients with hypotensive and hypovolemic states (decreased urine output, tachycardia, decreased CVP)
Patients require volume expansion
Isotonic solution examples
0.9% NS
Lactated Ringers
D5W
D5 0.225% NaCl
Hypotonic
Shifts fluid out of the intravascular compartment, hydrating the cells and interstitial compartment
Osmolarity is lower than serum osmolarity
Hypotonic solutions cause fluid to move into the cells
Hypotonic solutions
Indicated for patients with dehydration or hypernatremia
Hypotonic solution examples
0.45% NaCl (NS)
D5 0.45% NS
2.5% dextrose
When to use hypotonic solutions
If there is a need to administer water to patient
Cells are dehydrated
Maintenance fluids (not volume replacement!!!)
Caution: Hypotonic solutions may cause cardiovascular collapse due to decrease in vascular blood volume
Do not administer hypotonic solutions to clients at risk for third spacing, increased intracranial pressure (head injuries), liver disease, trauma or burn patients
Hypertonic
Draws fluid into intravascular compartment from the cells and interstitial compartment
Osmolarity is higher than serum osmolarity
Hypertonic fluids pull fluid from the cells into the vascular space
Fluid volume overload signs and symptoms: swelling (edema), high blood pressure, shortness of breath, rapid weight gain, full, bounding pulses, ascites, crackles in the lungs