Wuchereria bancrofti

• Common name of Wuchereria bancrofti

  Bancroft's Filarial Worm
• W. bancrofti‘s morphology

  minute, whitish and thread-like
• W. bancrofti‘s shape

  filariform in shape with a smooth surface.
• Both anterior and posterior portion are?

  tapering
• Male tail is?

  sharply curved ventrally
• female is

  Viviparous
• female is

  longer than male
• disease of W. bancrofti

  Lymphatic Filariasis
• Lymphatic Filariasis is caused by?

  the juvenile and adult worms.
• a certain proportion of the population

  living in these areas do not show any overt clinical

  manifestations of the disease or any mcf in their blood even

  though they are exposed

  ENDEMIC NORMAL
• persons in this stage have mcf

  in their blood but do not show any clinical manifestation of

  filariasis

  ASYMPTOMATIC STAGE
• caused by antigens released by

  female adult worms. Mcf cause no inflammatory changes.

  The condition is characterized by Filarial Fever,

  Lymphoedema, Lymphadenitis, adenolymphagitis.

  ACUTE FILARIASIS
• usually takes 10 to 15 years to develop.

  CHRONIC FILARIASIS
• most common feature. Caused by the

  obstruction of the lymph vessel of the spermatic cord

  and exudation from the inflamed testes and Epididymis

  hydrocele
• caused by a complex immune reaction

  of long duration and repeated super infection over

  many

  elephantiasis
• caused by the adult worms present in the lymphatic of the breast. Characterized by the presence of a firm solitary mass in the breast.

  Granuloma of the female breast
• urine shows chyle mixed with blood and

  occasionally with mcf. It is caused by the obstruction of

  lymphatic vessels of the kidney and the abdomen

  Chyluria
• it is the obstructive phase

  Chronic Filariasis
• Mcf are not found in the peripheral blood and the classical

  features of lymphatic filariasis are absent.

  OCCULT FILARIASIS
• it is most important manifestation of occult filariasis

  TROPICAL PULMONARY EOSINOPHILIA
• presence of adult worm in the anterior chamber of the eye

  LESS FREQUENT LESIONS
• give the diagnosis for W. bancrofti?

  1. Blood microscopy
  2. QBC (Heparinized capillary tube)
  3. Urine microscopy
  4. Knott's Concentration and Millipore or Membrane Titration Method
• treatment for W. bancrofti

  Diethyl carbamazine citrate(DEC)
• types of chronic filariasis:

  Hydrocele

  Elephantiasis

  Granuloma of the female breast

  Chyluria

  Lymph varices