Mb

• IS Mb an intracellular or extracellular protein.

  Intracellular.
• What is the role of Mb in humans.

  Oxygen diffusion.
• What type of alpha helixes does Mb have.

  Right handed.
• Which residues terminate the helixes.


  Proline.
• What is the Proximinal histidine residue called.

  F8.
• What is the distal histidine residue called.

  E7.
• What is the heam group made up of.

  1. Fe II
  2. Protoporphyrin IX
• Which histidine is bonded to the 5th coordinate position. 


  F8.
• What is the effect of the F8 bond.

  Pulls Fe II out of the plane.
• What are the two roles of E7

  1. Reduces affinity for CO
  2. Prevents Mb-O2-Mb formation
• What is the equation for Kd for Mb.

  [Mb*O2]/MbO2
• Describe the Oxygen binding curve.

  
• What is the value for Kd for Mb

  2.75 mm Hg
• What is the value for P50 for Mb

  2.75 mm Hg