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Animal Physiology
Renal Physiology
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Created by
Katie Mlodzik
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Cards (10)
Nephrons
Basic
functional
unit
of kidneys
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Vertebrate excretory systems
Kidneys filter out waste from
blood
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Romagnani et al. 2013: 'Renal progenitors: an evolutionary conserved strategy for kidney regeneration. Nature Reviews Nephrology 9: 137.'
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Nephrons
Similar across phyletic groups
Corpuscle
,
filtering
unit
Proximal
,
intermediate
&
distal
tubule
Excreting
unit
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Glomerular ultrafiltration
1.
Capillary
bed
2. High pressures in glomerular capillaries within
Bowman's
capsule
↑
filtration
3. Pressure modulated by juxtaglomerular apparatus (JGA)
4.
Cup-shaped
structure
5.
Granular
cells
6. Macula densa
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Tubular reabsorption
Highly
selective
Production of
hyperosmotic
urine
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Loop
of
Henle
Proportionally
larger
medullas
produce more
concentrated
urine
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Body fluid composition
90% ECF osmotic pressure from
Na+
&
Cl-
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Na+ load
Reflected by
ECF volume
ECF hypertonic
ECF volume
Blood pressure
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Vasopressin
Increases
water
reabsorption
in the
collecting
duct
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