Renal Physiology

    Cards (10)

    • Nephrons
      Basic functional unit of kidneys
    • Vertebrate excretory systems
      • Kidneys filter out waste from blood
    • Romagnani et al. 2013: 'Renal progenitors: an evolutionary conserved strategy for kidney regeneration. Nature Reviews Nephrology 9: 137.'
    • Nephrons
      • Similar across phyletic groups
      • Corpuscle, filtering unit
      • Proximal, intermediate & distal tubule
      • Excreting unit
    • Glomerular ultrafiltration
      1. Capillary bed
      2. High pressures in glomerular capillaries within Bowman's capsule filtration
      3. Pressure modulated by juxtaglomerular apparatus (JGA)
      4. Cup-shaped structure
      5. Granular cells
      6. Macula densa
    • Tubular reabsorption
      • Highly selective
      • Production of hyperosmotic urine
    • Loop of Henle
      • Proportionally larger medullas produce more concentrated urine
    • Body fluid composition
      90% ECF osmotic pressure from Na+ & Cl-
    • Na+ load
      • Reflected by ECF volume
      • ECF hypertonic
      • ECF volume
      • Blood pressure
    • Vasopressin
      Increases water reabsorption in the collecting duct
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