2. When an impulse arrives at the end of a neuron, the impulse causes sacs that contain neurotransmitters to fuse with the membranes of the axon. These sacs, called vesicles, release their contents into the synaptic cleft. The neurotransmitters then diffuse across the synapse, taking less than 1 millisecond to reach the dendrites of the next neuron, or the cell membrane of the effector