BMR (kJ) = Body weight (kg) x 1.0 x 24 hours x 4.2
BMR for Females
BMR (kJ) = Body weight (kg) x 0.9 x 24 hours x 4.2
Factors affecting BMI
Lean muscle mass
Energy required by the body to digest, absorb, and metabolize the nutrients consumed is estimated to be 10% of the daily energy intake
Thermic effect of food (TEF)
Estimated Energy Expenditure (EEE) is the total amount of energy in the body every day.
EEE (kJ) = BMR (kJ) + TEF (kJ) = energy expended through physical activity (kJ)
Calculate the energy balance (EB) for an individual
EB (kJ) = daily energy intake - EEE
Recommended Daily Intake (RDI)
Sufficient to meet the nutrient requirements of nearly all (97-98%) individuals in a particular life stage
Estimated Average Requirement (EAR)
This value would give 50% chance of developing a deficiency disease
Used as a minimum intake guide
Adequate Intake (AI)
Based on observed nutrientintake by a group of apparently healthy people with no deficiency
Tolerable Upper Intake Level (UL)
Highest daily nuturient intake level that will pose no adverse health affects to almost all individuals in the general population
As intake increases above the UL, the potential risk of adverse effects increases.
EstimatedEnergyRequirement (EER)
Needed to maintain current weight.
Identify organs involved in the ingestion and digestion of food/fluids along the gastrointestinal tract.
Mouth
Salivaryglands
Oesophagus
Stomach
Liver
Gall bladder
Pancreas
Smallintestineandlargeintestine
Rectum
Anus
Mouth function
Chewing of food (Mastication)
Increases SA of the food to be digested by digestive enzymes
Salivary glands functions
Adds saliva during chewing to moisten food and aid digestion through the addition of enzymes including salivary amylase
Salivary amylase in the mouth
Breaks down starch (form of carbohydrate) into maltose
Oesophagus
connects the mouth and stomach
food is moved by a process called peristalsis
Chemical digestion in stomach
Wall of stomach secrete mucus, HCL and gastric pepsin into the stomach.
2 Small intestine functions
Complete the digestion of macronutrients into their simple subunits
Absorb nutrient molecules into the blood or lymph (lined with villi to increase SA so more nutrient can be absorbed)
Mechanical digestion in the small intestine
Emulsification - breaks down large fat droplets into small fat droplets
increases SA, increases availability to enzyme
Describe the important of the gut microbiome synthesis of Vitamin K
required for blood clotting and healthy bones
Describe the important of the gut microbiome synthesis of short chain fatty acids (SCFA)
from the fermentation of soluble fibre, assists with:
mucus production
maintaining healthy cells in the lining of the gut (epithelial cells)
improves immune function
maintaining the correct pH
Infection effect on gut microbiome diversity?
Toxins become released which damage tissue and reduces the number of 'good' bacteria.
Food poisoning effect on gut microbiome diversity? (salmonella or e. coli)
Disrupts the gut microbiome. Research associated this with increased risk of irritable bowel syndrome.
Antibiotic effect on gut microbiome diversity?
A drug that kills bacteria, and is useful to fight of bacterial infection.
Antibiotics kill many 'good' bacteria in the gut. Individuals will often have diarrhoea as the microbiome is unable to play its normal role. But a diverse microbiome will allow fewer symptoms and recover quickly.
Lactose intolerance and coeliac disease are factors that intefere with the absorption of nutrients.
Lactose Intolerance
An individual who does not produce enough of the enzyme lactase. (lactase - responsible for the breakdown of lactose into glucose and galactose to be absorbed in the bloodstream)
If not digested, it will pass to the large intestine and will be consumed by the gut bacteria. -produce gas, causing pain, bloating, diarrhoea.
Management is through diet, removing or reducing dairy products consumption. Lactase enzyme tablets are available to consume prior to consuming lactose.
Coeliac Disease
A genetic disorder, an individual forms an immune response to gluten. - found in wheat, barley, oats.
Causes the villi within the small intestine to become flattened and damaged.
Damaged villi reduce SA availability for the absorption of nutrients.
All nutrients are affected, reduction in energy.
First symptom often related to iron-deficiency anaemia, and abdomen pain.
Management is following a gluten-free diet.
Proteins are a long chain of amino acids.
General structure of amino acids (made of carbon, hydrogen, oxygen, and nitroge)
Central carbon atom bonded to one hydrogen atom and the R-group.
The R-group is different for each of the 20 amino acids
The central carbon is bound to the amino group (NH2) and the carboxylic acid group