Save
Kaplan
Biochemistry
Chapter 6: DNA and Biotechnology
Save
Share
Learn
Content
Leaderboard
Learn
Created by
Keely Smith
Visit profile
Cards (23)
DNA can be denatured by conditions that disrupt
hydrogen
bonding and
base-pairing.
Commonly used to dentare DNA:
heat
,
pH
, and
chemicals
Once Denatured DNA is
single-stranded.
Euchromatin contains
genetically active
DNA.
Heterochromatin is
transcriptionally
silent.
Centromeres
are a region of DNA found in the center of chromosomes.
Centromeres
are sometimes referred to sites of constriction because they form noticeable
indentions.
In replication, DNA unwinds at points called
origins
of
replications.
Replication forks form on both sides of the origin, which increases the efficiency of
replication.
Helicase
unwinds DNA, generating two single-stranded template strands.
Nucleases are responsible for the
degradation
of
DNA
Topoisomerases
reduce torsional stress and reduce the risk of strand breakage.
DNA polymerases
are responsible for reading the DNA template, and synthesizing the new daughter strand.
DNA polymerase reads the template strand in the
3'
to
5'
direction.
DNA synthesizes a complementary strand in the
5'
to
3'
direction.
Primase
synthesizes a short primer in the 5' to 3' direction to start replication on each strand.
DNA ligase
seals the ends of DNA molecules together, creating one continuous strand of DNA.
Metastasis
is the migration to distant tissues by the bloodstream or lymphatic system.
Mismatch repair is in the
G2
phase of the cell cycle.
cDNA lacks
noncoding
regions
Noncoding
regions are
introns
Coding regions are
exons
Hybridization
is the joining of
complementary
base pair sequences.