Ascaris Lumbricoides

• Intestinal Nematodes

  ➢ Soil-transmitted helminths

  • Ascaris lumbricoides

  • Trichuris trichiura

  • Hookworm

  o Necator americanus

  o Ancylostoma duodenale

  o Strongyloides stercoralis

  ➢ Enterobius vermicularis

  ➢ Capillaria philippinensis
• ASCARSIS LUMBRICOIDES

  • Giant roundworm

  • Most common human intestinal nematode

  • Soil-transmitted helminths
• ASCARSIS LUMBRICOIDES

  Pathology:

  • Tissue reaction to the invading larvae

  • Intestinal irritation to the adult

  • Other complications due to heavy infection and extraintestinal migration
• ASCARSIS LUMBRICOIDES

  Biology:

  ❖ ADULT

  • Males 10-31cm

  • Females 22-35cm (200,000 eggs/day)

  • Large whitish to pinkish worms with smooth striated cuticles

  • Reside in small intestines
• ❖ EGGS

  • Infertile eggs are longer and narrower than fertile eggs

  • Infective stage: fully embryonated egg
• LIFE CYCLE

  ➢ Infective stage

  • embryonated eggs

  ➢ MoT- mouth

  ➢ Hepato-tracheal migration- 14days

  ➢ Adult development – 9 to 11 weeks

  ➢ Life span- 1 to 2 years

  ➢ Embryonated eggs can survive in the soil for few months to 2 years.
• Ascaris lumbricoides-

  Ascariasis

  ➢ Pathogenesis: Ascariasis

  ➢ Majority are asymptomatic

  • Lung infiltration

  • Asthmatic attacks

  • Edema of the lips
• ➢ Diagnosis

  • DFS

  • Kato-Katz technique

  • FECT ➢ Treatment

  • Single dose Albendazole (400mg)/Mebendazole (500mg)/Pyrantel pamoate (10mg/kg, max 1g); Ivermectin (200ug/kg)
• ➢ Prevention and Control- WASHED (Water, Sanitation, Hygiene Education, Deworming)