Metabolic Pathways

• Fermenation is the anaerobic degradation of glucose.
• In the preparatory phase of glycolysis ATP are consumed.
• In the payoff phase of glycolysis 4 ATP are produced.
• Net yield of 2 ATP per molecules of glucose converted to pyruvate.
• In the preparatory phase of glycolysis hexokinase and PFK-1 use ATP and make ADP.
• In glycolysis enolase releases a two waters.
• The metabolically irreversible reaction catalyzed by PFK-1 is what commits glucose to glycolysis.
• High ATP inhibits PFK-1
• Citrate inhibits PFK-1/.
• When ATP is low FBPase-1 is upregulated.