OCD genetic explanation

• OCD genetic explanations research

  • LEWIS (1936) observed that of his patients:
  • 37% of parents
  • 21% of siblings also had OCD
  • this suggests OCD runs in families and they're genetically vulnerable to developing it
• OCD genetic explanations diathesis stress model

  • certain genes may may them more likely to develop it but may needs some environmental stress / experience to trigger the condition
• candidate genes - OCD

  • Polygenic - caused by many genes
  • candidate genes create OCD vulnerability
  • some of the genes are responsible for the regulation of the serotonin system (synapse transportation)
  • the SERT gene (5-HTT) is linked to serotonin (neurotransmitter) and affects the trasnport of seratonin, causing lower levels of serotonin which is associated with OCD and depression
• candidate genes research - genetic explanation

  • TAYLOR (2013) analysed previous studies and found 230 genes that may be linked to OCD
  • genes linked to serotonin and dopamine levels are thought to have a role and are neurotransmitters linked to mood