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Spring 2024 FInals
med micro final
Influenza
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Created by
Shiva Parviz
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Cards (22)
Influenza is an
ssRNA
virus
FLu A: leads to
epi
and
pandemics
, has
animal reserviours
Flu B: can lead to
epidemics
, no
animal reservoirs
Flu C:
minor
respiratory dosease
Hemaggluination binds to the
polysaccharide
chains with
sialic acid
residues
Influenza
residues
determines to what
receptors
it binds to
Influenza attachment binds to
sialic
acid on
glycoproteins
flu incubates for
1-3
days
Flu infects
epithelial
cells in the
respiratory
tract
Flu is transmitted by sloppily making out with people (
aerosols
)
Flu has
malaise
,
non-productive
cough
Amantidine
and
Rimantidine
prevent uncoating
Zanamivir
is an
NA
inhibitor
Antigenic drift: change in
H
and N proteins,
gradual
over time
Antigenic shift is the
recombination
of viruses
Flu incubation
is
1-3
days
FLu recovery is
1
week
Flu reasons incubates in the upper
respiratory
Flu destroys epithelial and
mucus
secreting cells
FLu virus spreads into the
lower respiratory tract
FLu causes the
shedding
and necrosis of lung
epithelial
cells
Immune response causes the trigger of
interferon
and
lymphokine
release