503 vocab

• aspirin drug class

  antiplatelet agent; salicylate; NSAID
• acetaminophen brand name


  Tylenol
• celecoxib drug class

  NSAID, COX-2 selective; analgesic, nonopioid
• diclofenac activity

  reversible competitive inhibitor
• ibuprofen brand name


  Advil, Motrin
• meloxicam brand name


  Mobic
• amoxicillin + clavulanate brand name

  Augmentin
• budesonide + formoterol brand name


  Symbicort
• acetaminophen indication

  pain, fever
• celecoxib indication

  pain
• diclofenac MOA

  By reversibly inhibiting COX-1 and COX-2, NSAIDs inhibit the biochemical conversion of arachidonic acid to PGH2 which then prevents the downstream effects of prostanoids to prevent the inflammatory response and reduce pain signalling
• metformin brand name


  Glucophage, Glumetza, Riomet
• metformin + sitagliptin brand name


  Janumet
• lisinopril + hydrochlorothiazide brand name


  Zestoretic
• triamterene + hydrochlorothiazide brand name


  Maxzide
• valsartan + hydrochlorothiazide brand name


  Diovan HCT
• aspirin indication

  secondary prevention after acute coronary syndrome
• aspirin activity

  irreversible competitive inhibitor
• aspirin target

  COX-1
• aspirin target class and location

  oxidoreductase enzyme in platelets
• acetaminophen activity

  reversible competitive inhibitor
• acetaminophen target

  COX-1, COX-2, COX-3
• acetaminophen target class and location

  oxidoreductase enzyme in platelets in SMCs (COX-1), parenchymal cells (COX-2), CNS (COX-3)
• acetaminophen + codeine brand name


  Tylenol #3
• celecoxib brand name


  Celebrex
• celecoxib pharmacologic activity

  reversible competitive inhibitor
• celecoxib target

  COX-2
• celecoxib target class and location

  oxidoreductase enzyme in parenchymal cells
• diclofenac brand name


  Voltaren
• diclofenac indication

  pain
• celecoxib drug class

  NSAID, COX-2 selective; analgesic, nonopioid
• diclofenac drug class

  NSAID; analgenic nonopioid
• diclofenac target

  COX-1 and COX-2
• ibuprofen drug class

  NSAID; analgesic, nonopioid
• ibuprofen indication

  pain
• ibuprofen activity

  reversible competitve inhibtor
• ibuprofen drug target

  COX-1 and COX-2
• ibuprofen target class and location

  oxidoreductase enzyme in platelets and SMCs (COX-1) and parenchymal cells (COX-2)
• diclofenac target class and location

  oxidoreductase enzyme in platelets and SMCs (COX-1) and parenchymal cells (COX-2)
• meloxicam target class and location

  oxidoreductase enzyme in platelets and SMCs (COX-1) and parenchymal cells (COX-2)