Monoclonal Antibodies

    Cards (4)

    • Use of monoclonal antibodies: Therapeutics
      • mAbs can be used in theraputics to target specific cells like cancer cells
      • Method 1: Administering mAbs which bind to complementary specific antigens on cancer cell, preventing molecules that cause cell division from binding. Since mAbs aren't toxic, they won't harm the rest of the body
      • Method 2: Attaching a drug to a mAb which kills the cancer cell. The mAb directs the drug to the cancer cell, reducing the chances of the drug harming a healthy cells
    • Use of monoclonal antibodies: Diagnostics
      • mAbs can be used in medical diagnostic the formation of an antigen-antibody complex enables the condition to be detected
    • Monoclonal antibodies: Ethics
      • The development of mAbs for treatment involves delibrately infecting mice
      • During human trials, there has been reports of dangerous side effects and even death
    • What is a monoclonal antibody?

      Antibodies with the same tertiary structure, produced from cloned plasma cells