Metabolic processes of cells alter the internal environment, reducing the concentration of substrates, and increasing the concentration of products, which may be toxic
A good communication system is needed to ensure that different organs working together to perform the same function, such as excretion of waste work together effectively even if they are not adjacent to each other
1. Gap junctions may facilitate the movement of small molecules from cell to cell
2. Contact dependent communication may occur between signalling molecules in the plasma membrane of the signalling cells and receptor proteins present in the plasma membrane of the target cell
3. Paracrine cells secrete signalling molecules which diffuse locally through the extracellular fluid
Ectotherms are not able to control their body temperature using their metabolism; they rely on external sources of heat and their body temperature fluctuates with the external temperature
Some ectotherms have physiological adaptations to control body temperature, such as darker colours in colder climates and ability to control heart rate