Pharma: Cardio meds

• give 4 classifications of cardio meds ABC

  1. ACE Inhibitors and ARBS
  2. Beta blockers
  3. Calcium channel blockers
• Beta-blocker prefix -olol
• Calcium channel blocker prefix -dipine
• ace inhibitors prefix -pril
• ARBS prefix -sartan
• beta blocker

  indication: palpitations exceeding 100 bpm & hypertension

  examples: MAPSS

  Metoprolol

  Atenolol

  Propranolol

  Syraolol ⭐

  Sanaolol ⭐
• WOF syraolol = Psychosis
• beta blocker

  -what to check b4 giving? HR ⭐

  -A/e: Wheezing ⭐; bronchoconstriction = do not give to lung problem!

  -a/e: depression ⭐
• calcium channel blockers

  -indication: hypertension & ventricular rhythm problem (ECG)

  -ex. NAVD

  Nifedipine

  Amlodipine

  Verapamil - for VEntricular DIsrhythmia

  Diltiazem - for VEntricular DIsrhythmia
• calcium channel blockers

  WOF: - dizziness ⭐

  • no combination with grapefruit juice (juice is allowed with only Terazosin: for benign prostatic hyperplasia)
  • no combination with other meds --> risk for fatal hypotension
• ace inhibitors (angiotensin converting enzyme)

  -r/t RAAS -> bp regulation

  -ex. Captopril

  Enalapril

  Lisinopril

  Maxipril - s/e: good skin
• ace inhibitors

  -take b4 meals

  -s/e cough - expected but still report

  -a/e angioedema (facial edema) ⭐

  report !! - lips swelling - inc in size of tongue - report tall peak T wave = hyperKalemia
• ang ace inhibitors ay bawal sa mga buntis ! teratogenic
• ARBS (angiotensin receptive blockers) "-sartan"

  ex. valsartan telmisartan losartan

  -a/e: angioedema, hyperKalemia (lahat ng angiotensin like ACE)
• which drug can lead to urine discoloration?

  1. allopurinol
  2. acetaminophen
  3. phenytoin
  4. corticosteroids

  answer: 3