Immunology (2)

Created by

Jessica adejko

Cards (19)

Mononuclear phagocytes 
1. Circulate in blood for 8 hours
2. Migrate into tissues
3. Differentiate
NK cells 
Large lymphocytes
NK cells 
First line of defense against viruses
Target and kill infected cells
Produce various cytokines
Major types of dendritic cells 
4
Dendritic Cells 
Perform antigen capture
Perform antigen presentation
Perform T cell activation
Can produce ROS
Can produce interferons
Major cell groups of adaptive immunity
B lymphocytes
T lymphocytes
B lymphocytes
Mature in bone marrow
B cell receptor is a membrane bound antibody
Memory cells have a longer lifespan
Plasma cells produce antibodies
First encounter of antigen - divides rapidly into memory and plasma cells
T lymphocytes
Bone marrow derives but matures in thymus
Express T-cell receptor on membrane
In response to specific antigens, lymphocytes proliferate
Both B and T lymphocytes undergo clonal selection
Plasma (effector) cells 
Short lived
Mononuclear phagocytes
1. Circulate in blood for 8 hours
2. Migrate into tissues
3. Differentiate
NK cells 
Large lymphocytes
NK cells 
First line of defense against viruses
Target and kill infected cells
Produce various cytokines
Major types of dendritic cells
4
Dendritic Cells 
Perform antigen capture
Perform antigen presentation
Perform T cell activation
Can produce ROS
Can produce interferons
Major cell groups of adaptive immunity
B lymphocytes
T lymphocytes
B lymphocytes 
Mature in bone marrow
B cell receptor is a membrane bound antibody
Memory cells have a longer lifespan
Plasma cells produce antibodies
First encounter of antigen – divides rapidly into memory and plasma cells
T lymphocytes 
Bone marrow derives but matures in thymus
Express T-cell receptor on membrane
In response to specific antigens, lymphocytes proliferate
Plasma (effector) cells are short lived
Memory cells – long lived but don't take part in the initial immune reaction but respond to the second encounter
Both B and T lymphocytes undergo clonal selection