A lifelong condition in which the body does not produce enough insulin (or the insulin produced does not work), resulting in very high and dangerous blood glucose concentrations unless treated
People who have had diabetes for a long time and whose blood glucose concentration is not tightly controlled
Are at risk of developing long-term complications including eye damage (and blindness), heart disease and strokes (circulatory diseases), and kidney damage
The pancreas is an organ that produces insulin, glucagon, somatostatin, and digestive enzymes.
Glucose enters the bloodstream from food or liver glycogen breakdown.
When blood glucose levels are low, the pancreas releases glucagon into the bloodstream.
Glucagon stimulates the liver to convert stored glycogen back into glucose, which increases blood glucose levels.
Diabetes
A common medical condition in which the blood glucose control mechanism fails. The pancreas does not make enough insulin to maintain the blood glucose concentration at the normal level.
Usually occurs early in life when the pancreas stops producing insulin, which then has to be taken as medicine throughout life. This is usually in the form of insulin injections and by a carefully controlled diet where the intake of carbohydrates is carefully monitored.
A progressive disease linked to lifestyle factors and obesity, where the pancreas gradually produces less insulin, which in the early may be controlled by diet but later may also require insulin injections.
The numbers of people with diabetes is rising, in particular those suffering from Type 2 diabetes. This could be due to a decline in the number of people following a healthy lifestyle (healthy diet and exercise) and so this can cause their insulin to not function correctly.