215 Week 1 Review

• As LET ____________, the RBE ______________. 

  Increases , Increases
• Tissue is _______ radiosensitive under high oxygen conditions and _________ radiosensitive under hypoxic conditions. 

  More , Less
• A _________ response to radiation is directly proportional to the dose received. 

  linear
• If a response to radiation is expected, no matter how small the dose, then that dose-response is _________________. 

  nonthreshold
• Radiation induced genetic damage follows a ___________________ dose-response relationship. 

  linear nonthreshold
• LET: Linear energy transfer


  Measure of the rate at which energy is deposited as a charged particle travels through matter or soft tissue.
• OER: Oxygen enhancement ratio


  Dose of radiation that produces a given biologic response under anoxic conditions divided by the dose radiation that produces the same biologic response under aerobic conditions. (the prescense of oxygen)