Toxicology

• Codon


  A sequence of three DNA or RNA nucleotides that corresponds with a specific amino acid or stop signal during protein synthesis
• Gene-environment interaction in Siamese cats


  A gene that controls pigment production is only able to function at the lower temperatures of the extremities. The gene is silent at high temperatures.
• Egg incubation temperature in reptiles


  Modulates the aromatase activity and therefore determines the sex of the embryo: very high and very low temperature (eggs on top and bottom layers in the nest) favour males, middle range temperatures are associated with high percentage of females.
• Mechanisms involved in the regulation of gene expression


  • Regulation of chromosome condensation
  • Regulation of mRNA degradation
  • Regulation of protein degradation
  • Regulation of translation
  • Regulation of replication
• Genetic code


  More than one codon may specify a particular amino acid, however no codon specifies more than one amino acid