self and non self

• human leucocyte antigen 


  displays antigen on its surface to the immune system
• innate immune response 


  barriers, pattern recognition receptors, cytokines, NK cells, dendritic cells, phagocytosis
• cytokines


  regulate and coordinate immune response
• interferons 


  viral infections, act as a warning system
• interleukins


  secreted by macrophages and lymphocytes, regulate interactions between various parts of the immune system
• phagocytosis


  engulf, monocytes/macrophages, dendritic cells, neutrophils
• NK cells 


  role in rapid response, respond to infected cell without the presence of an MHC molecule, release perforin and granzyme
• cell-mediated immunity 


  each T cell has a unique T cell receptor, TCR binds with MHC-presented antigen
• cytotoxic T cells


  recognise and destroy cells with a foreign antigen
• helper T cells


  enhance the immune response
• suppressor T cells


  suppress the immune response
• memory T cells 


  remain in the lymphatic tissue for years, important in secondary immune response