MDL244 questions

• Reagent contamination will not cause false positive Rh testing results. true or false

  false
• The (MHC) refers to a cluster of genes that are involved in graft rejection and the immune response.
• Because of its immunogenicity, the D antigen is the most clinically important antigen of the Rh blood group system.


  True
• The antiglobulin phase of serologic testing uses anti-human globulin reagent to detect binding of IgG antibody to antigen on the red cells.


  True
• Precautions


  Procedures that reduce the risk of exposure to blood borne infections
• MSDS


  Manufacturer information regarding hazardous materials/chemicals
• Validation


  Testing performed to evaluate whether an instrument or system correctly does what it is designed to perform
• Type and Screen


  ABO/Rh testing and a screen for unexpected antibodies
• Acquired B

  Considered a type of ABO discrepancy in Group A individuals where additional antigen reaction is present
• Auto Control


  Test method where the patient's cells and patient's plasma are used
• Mixed Field Agglutination

  Mixture of agglutinated and non-agglutinated red cells, indicating a possibility of 2 or more cell populations
• Clinically Significant Antibody

  Antibodies that react at 37 degrees and are capable of causing decreased RBC survival in vivo
• Crossmatch


  Compatibility testing using donor cells and patient plasma
• Adsorption


  Purposely attaching antibody to RBC in an attempt to remove that antibody from plasma
• Indirect Antiglobulin Technique (IAT)

  Use of Anti-Human Globulin reagent to detect RBC-bound antibodies
• Elution


  Removal of bound antibody from the RBC surface into a solution for further testing
• Which of the following reagents may be used to potentiate the reactivity of weak antibodies?

  albumin, PEG, LISS
• If patient Mr. P's blood type is A Positive, specify all blood types of RBCs that would be compatible for transfusion.

  A Positive, A Negative, O Positive, O Negative
• Which of the following antibodies characteristically react ONLY at the AHG phase of testing?

  Anti-Fya, -Jka, and -K

  
  

  (Duffy, Kell, Rh, Kidd, Ss)