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Paper 1
B3 Infection and Response
More on Monoclonal Antibodies
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What is the name for the antigens which cancerous cells have on their cell membranes which normal cells don't have?
Tumour markers
How
are monoclonal antibodies used to fight cancer?
Anti-cancerous drugs are attached to monoclonal antibodies which bind with the
tumour
markers on cancerous cells and
kills
them
How are cancer patients given anti-cancer drugs attached to monoclonal antibodies?
Through a drip
What
other uses do monoclonal antibodies have?
Bind
to hormones and other chemicals in
blood
to measure their levels
Test
blood
samples for
pathogens
Locate specific molecules in
cells
or
tissues
How
are monoclonal antibodies used to locate a molecule inside a tissue or cell?
Monoclonal antibodies
which bind to the specific
substance
are produced
Antibodies are then attached to a
fluorescent dye
If the specific molecule is present, the antibodies will attach to it and can be detected using the
dye
What are the disadvantages of monoclonal antibodies?
Can cause more
side effects
than originally expected