Biological catalysts that increase the rate of metabolic reactions
Factors affecting enzyme function
Temperature
pH
Substrate concentration
Enzyme concentration
Effect of temperature on enzyme-controlled reactions
As the temperature increases, so does the rate of reaction
Once the temperature exceeds the optimum, the enzyme denatures and the rate of reaction decreases
Why temperature increases rate of enzyme-controlled reactions
As the temperature increases the particles have more kinetic energy, this increases the chance of collisions between molecules being successful and leading to a reaction
Effect of high temperature on enzyme function
The active site will be distorted as the enzyme denatures and so it will no longer fit the substrate
Effect of pH on enzyme-controlled reactions
The rate of an enzyme catalysed reaction is fastest at the optimum pH
If the pH is too high or low, the enzyme will work less efficiently and the active site may be denatured at extremes of pH