Night workers engaged in shift work experience period of reduced concentration around 6am (circadian trough), increasing likelihood of mistakes and accidents.
Circadian rhythms have revealed certain peak times which drugs are most effective; as they coordinate main bodily processes, which has an affect on pharmokinetics. This has led to development of guidelines for timing of various drugs eg. anti-cancer, cardiovascular, respiratory, anti-ulcer, anti-epileptic.
*Demonstrated poor methodology in studies of circadian rhythms eg. Siffre. Were able to adjust participants' rhythms between 22-28 hours with dim lighting; suggesting artificial light used in Siffre's study had an affect on what was being measured.
Individual differences; some people are 'owls' (displaying preference for sleeping late and waking late), whilst others are larks' (preference for sleeping early and waking early).
Infradian and ultradian rhythms - limitation of evolutionary theory:
If too many females cycled together, would produce competition for highest quality males; avoidance of synchrony would appear to be better adaptation for real life menstrual cycle.
Research support for the significance of REM. They monitored sleep patterns of 9 adults using EEGs, found that REM activity was highly correlated with dreaming. When they were woken up during REM, participants could recall dreams very accurately. Replications have shown same findings.
BRAC (basic rest activity cycle) theory suggests cycles during sleep occur during wakefulness; 90 mins of alertness, followed by short spell of physiological fatigue.
Supports effectiveness of BRAC developed from research into ultradian rhythms. Professional/best violinists found to practice in 3 x 90 min sessions during course of day, w/ a break to recharge.
changed mice feeding patterns, found to alter circadian rhythms in liver cells by up to 12 hours. Peripheral oscillators acting independently from endogenous pacemakers (such as SCN).