Chromosome structure mutations include duplication, deletion, inversion and translocation.
Duplication is where a section of a chromosome is added from its homologous partner.
Deletion is where a section of a chromosome is removed.
No other chromosome is affected.
Inversion is where a section of chromosome is reversed.
Translocation is where a section of a chromosome is added to a chromosome Which is not its homologous partner.
The substantial changes in chromosome mutations often make them lethal