Seizures - A sudden, uncontrolled electrical disturbance in the brain.
Seizures - can cause changes in the behavior, movements or feeling, and in levels of consciousness.
SYMPTOMS OF SEIZURES
High fever, associated with an infection such as meningitis
Lack of sleep
Flashing lights, moving patterns or other visual stimulants
Low blood sodium (hyponatremia), which can happen with diuretic therapy
HOW TO HELP SOMEONE WHO HAS GRAND MAL SEIZURE
Ease the person to the floor.
Turn the person gently onto one side. This will help the person to breathe.
Clear the area around the person of anything hard or sharp. This can prevent injury.
Put something soft and flat, like a folded jacket, under his or her head.
Remove eyeglasses.
Loosen ties or anything around the neck that may it hard to breathe.
Time the seizure. If the seizure lasts longer than 5 minutes, call for medical expert help.
ANTIEPILEPTIC DRUGS (SEIZURES)
Sodium valproate
Carbamazepine
Lamotrigine
Levetiracetam
Topiramate
ANTI-EPILEPTIC DRUGS SIDE EFFECTS (SEIZURES)
Drowsiness
Lack of energy/fatigue
Headaches
Uncontrolled shaking (tremor)
Hair loss or unwanted hair growth
Swollen gums
GI problems
ANTI-EPILEPTIC DRUGS SERIOUS SIDE EFFECTS (SEIZURES)
Unsteadiness
Poor concentration
Nausea or feeling of being sick
Suicidal thoughts
Thrombocytopenia, leukopenia
Rashes/anaphylaxis/serious skin conditions
Agitation
Phenytoin - the first anti-seizure medication
Phenytoin - improves evidence of seizures by interfering with sodium channels in the brain, resulting in a reduction of sustained high-frequency neuronal discharges.
Tonic-clonic, Psychomotor - where PHENYTOIN is indicated for
PHENYTOIN SERIOUS SIDE EFFECTS (SEIZURES)
Toxic epidermal necrolysis (TEN)
Steven-Johnson syndrome (SJS)
Rash, facial swelling, fever, lymphadenopathy
Acute hepatotoxicity
Thrombocytopenia
Leukopenia
Granulocytopenia
Agranulocytosis
Pancytopenia with or without bone marrow suppression
Nystagmus
Ataxia
Slurred speech
Decreased coordination
Somnolence
Mental confusion
PHENYTOIN BLACK BOX WARNING
should not exceed 50 mg per minute in adults and 1 to 3 mg/kg/min (or 50 mg per minute, whichever is slower) in pediatric patients because of the risk of hypotension and cardiac arrhythmias.
Serum drug monitoring - a monitoring required for PHENYTOIN as its toxicity may produce delirium, psychosis, or encephalopathy
Heart block - where PHENYTOIN is contraindicated
Epilepticus - what may occur due to the abrupt discontinuation of PHENYTOIN
Gabapentin - a drug indicated as an adjunct treatment for partial seizures, but is most commonly used to treat neuropathic pain.
GABAPENTIN SIDE EFFECTS
Dizziness
Somnolence
Ataxia
GABAPENTIN SERIOUS SIDE EFFECTS
Suicidal thoughts
Worsening of depression
Unusual mood and behavioral changes
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), also known as multiorgan hypersensitivity.
Fever
Rash
Lymphadenopathy
Fall precautions - should be considered when taking GABAPENTIN, especially those in elderly patients
Peripheral edema, Ataxia - diseases/illness caused by GABAPENTIN in older patients