Pasteur was the first to suggests that Germs cause disease
He was employed in 1857 to explain why sugar beet went sour in alcohol
He blamed germs and proved it
In 1861, he published his germ theory.
Impact of Germ theory
First met with scepticism because people couldn't believe tiny microbes caused disease.
It didn't help germ responsible for each disease had to be identified individually
It then soon gained popularity in Britain
Inspired Joseph Lister to develop antiseptics
Proved John snow findings about cholera which put pressure on the government to pass the 1875 public health act.
Robert Koch
Built on Pasteur's work by linking specific diseases to the particular microbe that caused them.
He identified anthrax spores (1876) and bacteria that cause tuberculosis (1882) and cholera (1883)
He used agar jelly then used dyes to stain the bacteria and employed newly invented photograph to record his findings.
Florence Nightingale
Born in 1820
Studied to become a nurse in 1849
When the Crimean war broke out, she was sent to nurse hospitals (1853)
She took 38 nurses and using training she had learnt from training in Europe.
Nightingale made sure all wards were clean and hygienic and water was clean.
Death rate went from 42% to 2%.
Nightingale impact
In 1859, she published a book on notes of nursing. This explained her methods and emphasised hygiene.
Public raised 44,000 to help her training nurses, she created the Nightingale School of Nursing.
By 1900, there were 64,000 trained nurses.
In 1919, the nurse registration act was passed. This made training compulsory.
Anaesthetics
Nitrous oxide was a possible anaesthetic but was ignored. There was a public demonstration in 1845 but had bad luck to pick a patient unaffected by nitrous oxide.
In 1842, Crawford Long discovered ether to have anaesthetic qualities of ether but didn't published his work. Ether was irritant and fairly explosive.
James Simpson discovered the effects of CHLOROFORM in 1847.
Queen Victoria gave birth to her eight child using chloroform in 1853.
Anaesthetic effect
Led to longer and more complex operations. This was because surgeons found out that unconscious patients were easier to work on.
Longer operations led to higher death rates from infection because they didn't know poor hygiene spread disease.
Joseph Lister
Used carbolic acid in operating theatres in the early 1860s and he reduced infection rates.
Lister heard about the germ theory in 1865 - he realised germs could be in the air , or on surgical instruments or peoples hand. He started using it on instruments and bandages.
The use of antiseptics reduced deaths rate from as high as 50% in 1864-66 to around 15% in 1867-1870.
Allowed surgeons to operate with less fear of patients dying from infection.
Cholera
Reached Britain in 1831. By 1832 it was an epidemic and 21,000 people died that year.
Spread when infected sewage gets into drinking water.
Best theory at the time was miasma.
John Snow
Showed connection between contaminated water and cholera.
When Cholera broke out in Broad Street area of London in 1854, Snow set out to test his theory.
He interviewed people living in Broad Street and made a map showing where the cases of disease where.
His investigation showed all victims used the same water pump on broad street. He convinced local council to remove the handle from the pump.
Discovered a nearby cesspit had its waste leaked into the water supply.
First Public Health Act (1848)
1848
Act set up a central Board of Health and let local councils set up their own boards of health.
Limited because very few people chose it and those that did refused to spend money.
Second reform act
1867
Because Snow discovery of the link between dirty water and cholera.
Gave an addition of 1 million working class men the vote.
Now that they had the vote, they could put pressure on government to listen to concerns about health
3rd Public health act
1875
Appoint health inspectors and sanitary inspectors who made sure that laws on things like water supplies and hygiene's were being followed
Maintain sewage system to prevent further cholera outbreak