miRNA-humans

• 1. in mammals the miRNA is not fully complimentary to the target mRNA- it is less specific than siRNA so it targets more than one mRNA molecule
• 2. miRNA associated with proteins and bins to target mRNA in the cytoplasm
• 3) miRNA protein complex physically blocks translation of target mRNA
• 4. the target mRNA moves into a processing body to be stores or degraded