70% of OCD sufferers experience both obsessions and compulsions combined. However, 20% experience just obsessions alone and 10% experience just compulsions alone.
Sufferers of OCD adopt cognitive strategies to deal with their obsessions. For example, sufferers with religious obsessions may pray over and over, to reduce their feelings of being immoral.
Sufferers of OCD know that their obsessions and compulsions are irrational and experience selective attention directed towards the anxiety-generating stimuli (similar to the selective attention found in phobias).
Sufferers may attempt to avoid situations which might trigger compulsions. They try to manage their OCD for example, people who compulsively hand wash may avoid taking out bins or going outside where germs may be present. This can then interfere with their lives.
Genetic explanations have focused on identifying particular genes which are implicated in OCD. It is known as a polygenic which means there are multiple genes that might be involved with the development of OCD.
Associated with the production and regulation of the neurotransmitter dopamine. One variation of the COMT gene results in higher levels of dopamine and this variation is more common in patients with OCD, in comparison to people without OCD.
Linked to the neurotransmitter serotonin and affects the transport of the serotonin (hence SERotonin Transporter), causing lower levels of serotonin which is also associated with OCD (and depression)
OCD is also known to be polygenic. This means that OCD is not caused by only one gene but multiple/ combination of genes that together increase vulnerability.
Classic study by Lewis (1936) observed OCD in patients and found 37% have parents with OCD and 21% had siblings with OCD. This suggested that OCD can run in families.
MZ twins have a higher concordance rate for OCD than DZ twins. Billet et al (1998) 68%MZ and DZ 31%.
Certain genes leave some people more likely to develop mental disorder but is not certain. Instead, it is suggested that certain environments are most likely to trigger the development of the condition.
Taylor (2013) analysed findings of previous studies and found evidence of up to 230 different genes that may be involved with OCD development. These include the action of dopamine as well as serotonin both neurotransmitters believed to have a role in regulating mood.