Learning through association. Animals, including humans, have innate reflexes consisting of an US and an UR.
Pavolv's research - on dogs.
Pavlov placed salivation tubes in the cheeks of dogs to collect saliva.
The US of food elicits the UR of salivation.
He noted the salivation amount from each dog first with just the food, and then in each pairing with the bell.
Through repeated pairings, the NS of the bell became associated with the US of food, so the bell became a CS, eliciting the CR of salivation.
This shows that a neutral stimulus can come to elicit a learned response through association.