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MAGNETIC RESONANCE IMAGING
- A
computer-based cross-sectional
imaging modality
MAGNETIC RESONANCE IMAGING
-The use of
magnetic field
and
radio waves
to obtain a mathematically reconstructed image
MAGNETIC
RESONANCE IMAGING
- Originally called
Nuclear Magnetic Resonance
ADVANTAGES OF MRI
Best
low
contrast resolution
o Main advantage
o Rationale:
X-ray attenuation
coefficient in
soft
tissue – differ by <
1
% (in same tissue)
Spin density & T1
– differ by
20-30
% (in same tissue)
T2
– differ by
40
% (in same tissue)
No
ionizing
radiation
Direct
multiplanar
imaging
No
bone
or
air
artifact
Direct
flow
measurements
Totally
noninvasive
Contrast
media not required
MRI CONTRAINDICATION
Cardiac pacemaker
Aneurysm clips
Claustrophobia
Metallic fragments
in the eye
Cochlear implants
Internal drug infusion pumps
Neurostimulators
Bone growth stimulators
MRI
Provides sectional images
No
superimposition
of structures
Clearly
demonstrates structures even
without
contrast
media
Can resolved relatively small contrast
differences among tissue
Contrast
depends on the
interaction
of
matter with
electromagnetic
forces
CONVENTIONAL
Provides
“flat”
image
Structures are
superimposed
Contrast media
is required to clearly
distinguished one anatomic structure or
organ from one another
Limited
in its ability to distinguish types of
tissue
Cannot detect
small
attenuation changes
Can only distinguish air, fat, bone, soft
tissue
, and
metal
Contrast depends on differences of
x-ray
attenuation
1940’s
Felix
Bloch
and Edward
Purcell
first
discovered the
properties
of magnetic
resonance
MRI spectroscopy
: technique they used for
analysis of
complex
molecular structures
and
dynamic
chemical processes
1952
Bloch
and
Purcell
shared a
Nobel Prize
in
Physics
1971
Raymond Damadian
showed that the
relaxation
time of water in a tumor differed from the
relaxation
time of water in normal tissue
Investigated
excised rat
tissue
He reported that there were significant
differences between
normal
rat
tissues and
tumors
1975
Damadian
obtained the first
animal
images
1970s
MRI
was progressing
rapidly
1978
The
first human head scans
were obtained
Followed by
first human body scans
INDOMITABLE
Original name of the first
MRI
machine
ANTENNA
Device for
transmitting
or
receiving
radio
wave
ARTIFACTS
Spurious
finding in or
distortion
of an image
ATTENUATION
Reduction
in energy or amount of a
beam
of
radiation
when it passes through
tissue
or
other
substances
COIL
Single
or
multiple
loops of wire designed to
produce a
magnetic field
from
current
flowing
through the wire
CLAUSTROPHOBIA
The fear of having no escape and being in
closed or small spaces or
rooms
CRYOGENIC
- Relating to extremely
low
temperature
DIFFUSION
Spontaneous random
motion
of
molecules
in
a
medium
FAT SUPPRESSED IMAGES
Fat tissue in the image is made to be of a
lower, darker
signal
intensity
FREE INDUCTION DECAY
Signal emitted by tissue after RF excitation
GATING
Technique used in reducing
motion artifacts
GRADIENT ECHO
Fast pulse sequence
Often used with
3D
imaging to generate
T2-
weighted
images
GRADIENT MAGNETIC FIELD
A change in the
intensity of a magnetic field
in space
Unit:
mT/cm
GYROMAGNETIC
RATIO
A
constant, specific ratio
for each
nucleus
Half-life
in
MRI
Unit:
MHz
/T
Hydrogen
:
43 MHz
/T
o
Most abundant element
in the body
(
60
%)
INVERSE RECOVERY
Standard pulse sequence available in most
MRI imagers
Used for
T1-weighted
images
LARMOR FREQUENCY
- The frequency at which a
nucleus
precesses in the magnetic field
Unit:
MHz
MAGNETIC MOMENT
A
force created
when
magnetic dipole
is in a
magnetic
field
The
inherent magnetism
Unit: T
MAGNETIZATION
The
large-scale macroscopic
magnetic
moment
resulting from many
nuclear
magnetic
moments
NET MAGNETIZATION
Magnetic moments of
individual
hydrogen
nuclei aligned in the
external
magnetic field
PERFUSION
Flow of blood through
vessels
of an
organ
or
anatomic
structure
PRECESSION
The wobble of the
rotational
axis of a
spinning
body about a
stationary
axis
Describes a
cone
Rate of
precision
: increases as
MF strength
increase
RADIO FREQUENCY
(RF)
Electromagnetic
radiation having a
frequencies from
0.3kHz to 300 GHz
RF range in MRI:
1-100
MHz
RAW DATA
Information obtained by
radio reception
of
the
MRI
signal as stored by a
computer
RELAXATION
Returning to equilibrium
RELAXATION TIME
The
time required for return
SPECIFIC ABSORPTION RATE
(
SAR
)
The
power
absorbed during
RF
irradiation
Unit:
W/kg
RESONANCE
Transfer of
vibrating energy
from one
system to another
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