Limbic zft

• Limbic system is involved in olfaction feelings long term memory and behavior ans function
• limbic system is composed of amygdalla hippocampus anterior thalamic nuclei cingulate gyrus and entorrhinal cortex
• limbic is responsible for feeding fleeing feeling fighting and sex
• Mesocortical pathway:Ventral tegmental area projects to prefrontal cortex decreased activity leads to negative symtpoms antipsychotics have limited effect
• mesolimbic: ventral tegmental area projects to nucleus accumbens increased activtiy has positive effects antipsychotic first target
• nigrostriatal: subtansia nigra to dorsal striatum has motor control decreased activity shows extrapyramidal symptoms affected by antipsychotics
• tuberinfundibular hypothalamus to pituitary regulates prolactin secretion decreased activity equals increased prolactin affected by antipsychotics