Cerebellum

• modulates movement coordination and balance
• controls ipsilateral proprioceptive movements via inferior peduncle
• deep nuclei inclue globose dentate fastigal and emboliform
• medial cerebellum( vermis) controls axial and proximal limb musculature bilaterally
• lateral cerebellum controls distal limb musculature ipsilaterally
• Basal ganglia is responsible for voluntary movement and posture
• provides negative feedback to cortex to fix movement
• Striatum : putament and Caudate
• lentiform :globus pallidus and putamen
• direct pathway : cortical input via glutamate stimulates gaba release from striatum which inhibits gaba release from gpi which activates thalamus
• indirects pathway: cortical input via glutamate receptors which stimulates gaba release from striatum which INHIBITS gaba release from gpe which activates subthalamic nuclei which stimulates gaba release from the gpi inhibiting the thalamus
• Dopamine activates direct and inhibits indirect via D1 receptors to direct and D2 to indirect