A strength of research into circadian rhythms is practical application to drug treatments.
For example, circadian rhythms coordinate the body's basic processes (e.g. heart rate, hormone levels) with implications for pharmacokinetics.
Research shows there are times during the day/night when drugs are more effective, which has led to guidelines being developed for the timing of dosing for a range of drugs including treatments for cancer and epilepsy.
This strengthens both the applicability and support for research into circadian rhythms as it may have real-life medical benefits.
A limitation of research into circadian rhythms is poor control in Siffre's cave study.
For example, researchers questioned whether having access to artificial lights and cracks in the caves meant that Siffre hadn't eliminated all exogenous zeitgebers (light).
This suggests that results he collated could've been influenced by extraneous variables, not truly measuring the influence that the SCN had on regulating a circadian rhythm.
This weakens both the internal validity and support for research into circadian rhythms as Siffre may have ignored an important confounding variable.
Another limitation of research into circadian rhythms is that individual differences may be an influence on results.
For example, an issue complicating the generalisation of findings from studies of the sleep/wake cycle is that individual cycles can vary from 13 to 65 hours.
Also, Duffy found some people display a natural preference for sleeping and rising early ('larks') but others prefer the opposite ('owls'), and that there are age differences in sleep/wake patterns.
This weakens both the validity and support for research into circadian rhythms as findings may not fully represent individual differences within the population.