Gram negative bacteria

• Pseudomonas aeruginosa


  Gram-negative, aerobic rod belonging to the bacterial family Pseudomonadaceae
• Pseudomonas aeruginosa


  • Produces the blue-green pigment pyocyanin
  • Free-living bacterium, commonly found in soil and water, although it can be found on the surfaces of plants and animals
  • Emerging opportunistic pathogen of clinical relevance, that can lead to fatality
• Symptoms of Pseudomonas aeruginosa infection

  • Pneumonia
  • Urinary tract infections
  • Surgical wound infections
  • Blood stream infections (bacteraemia)
• Cystic fibrosis (CF) patients

  Pseudomonas aeruginosa is particularly frequent as a cause of chronic respiratory infection
• The overall rate of Pseudomonas spp. bacteraemia in England, Wales and Northern Ireland was 7.8 per 100,000 population in 2018
• There was a 22.2% increase in Pseudomonas spp. bacteraemia between 2009 and 2018
• The most commonly identified species in blood is Pseudomonas aeruginosa (80%)
• In England, Pseudomonas aeruginosa has dual resistance to gentamicin, ciprofloxacin, meropenem, piperacillin/tazobactam, Imipenem, tobramycin, ciprofloxacin and ceftazidime
• Pseudomonas aeruginosa is more commonly reported among those aged 75 years and older, especially among males