ACCP YEAR 1.

• When to use adrenaline? (1:1000).

  Anaphylaxis or threatening asthma
• Class of adrenaline


  Sympathomimetiend and agonist of a1, b1 and b2 receptors. A1 responsible for vaso constriction. Leads to a resistance in vessels and bp to rise. b1 found in the heart, b2 found in the lungs. b1 contract the heart, b2 bronhchodialtion. Inotropic (contraction) and chronotropic (heart rate) effects.
• Adrenaline dose


  IM, antero-lateral aspect of thigh. 500mcg - 1/2 a ml.
• Aspirin indications


  Clinical evidence of ischaemia or MI.
• Class of aspirin 


  Non steroidal anti-flammotory with anti-platelet propeties. Inhibits enzymes cyclooxygenase 1 and 2 (COX-1 and 2). Resposnivle for producing hormone like substances clled prostaglandins. COX 1 -> Producing stomach lining. COX 2 - Thromboxane production. If impaired prevents platelets sticking together.
• Aspirin dose


  300mg tablet
• Side affects of aspirin

  Increased risk of gastric bleeding and wheezing.
• Contraindications of aspirin


  Allergy, under 26, gastrointestinal bleeding, haemophilia or clotting disorders, jaundice
• Glucagon indications 


  Hypoglycaemia
• Medication class of glucagon

  Hormone relased from the alpha cells of the pancreatic islets of langerhans. Released to raise glucose and a catabolic hormone. Counterbalance to insuline. 1mg in 1ml IM.
• Glyceryl trinitrate (GTN) indications

  Cardiac chest pain due to angina or MI. Breathless due to pulmonary oedema and cocaine toxicity.
• Class of medication for GTN.

  Organic nitrate and vasodilating agent. Relaxes smooth muscles arteriolar and venous dilation thus reducing cardiac preload and afterload.
• Side affects of GTN and dose

  400mcg. Headaches and dizziness, hypotension - check bp.
• Ipratropium bromide indications


  Astmha or COPD exacerbation unresponsive to salbutamol
• Ipratropium bromide class of medication

  Antichlinergic. Antagonist of muscarinic acetylchloine receptors. Inhibits parasympathetic system in the airway to generate bronchial secrations and constriction
• Naloxone indiactions and class of medication

  Reverse opiod toxicity. opiod receptor atangonist. Dose IM 300mcg every 3 mins.