Injuries can affect the myelin, the axons, or both
Rarely is the myelin involved without at least some involvement of the axon (and vice versa)
Electrodiagnostic testing
Can determine what type of nerve injury exists, how severe the injury is, and where the injury is located
Classification of nerve injuries
Useful for understanding their pathological basis, making decisions on management, and predicting the prognosis for recovery
Seddon's classification of nerve injuries
Neurapraxia
Axonotmesis
Neurotmesis
Neurapraxia
Conduction block - only the myelin is affected
Axonotmesis
Anatomical disruption of the axons and their myelin sheaths, but the connective tissue layers of the nerve including the endoneurial tubes remain intact
Neurotmesis
Complete nerve injury involving the myelin, axon, and all supporting structures
Clinical examination and neurophysiology assessment may be the same for axonotmesis and neurotmesis, yet there is a clear difference in prognosis and management
Sunderland's 5 degrees of nerve injury
Based on increasing anatomical disruption of the nerve trunk and distinguishes injuries where the nerve trunk is in continuity but there is damage to endoneurium and perineurium
Strength-Duration (S-D) Curve
Relationship between the strength of a stimulus and its duration for producing minimal excitation
Constant-current stimulator
Current output set by the therapist will remain the same, voltage output would change with change in tissue impedance
Constant-voltage stimulator
Voltage output set by the therapist will remain the same, there will be change in the current with change in tissue impedance
Equipment required for S-D Curve
Low frequency generator
Moist saline pad
Electrodes
Leads
Bandage
Plastic protectors
D Curve test application
1. Apply longest stimulation first and increase until minimal contraction
2. Shorten impulse and increase intensity as required
3. Use minimal contraction to detect changes
Normal S-D Curve
Impulses of longer duration produce response with same strength, shorter durations require increased strength
Complete denervation S-D Curve
Steep rise and shift to the right, no response to very short impulses
Partial denervation S-D Curve
Kink where innervated and denervated fibers respond differently, indicates proportion of denervation
Rheobase
Lowest intensity with maximum pulse duration (100ms+) that just stimulates muscles or nerves
Chronaxie
Minimum time for which a current of intensity twice rheobase will cause contraction
Utilization time
Time taken by a stimulus of rheobasic strength to excite the nerve and produce a minimal muscle contraction