GENE EXPRESSION EXAMQS

• Describe how alterations to tumour suppressor genes can lead to the development of tumours [3]

  increased methylation of tumour supressor genes

  tumour suppressor genes are not transcribed

  results in rapid/uncontrolled cell division
• Explain how increased methylation could lead to cancer? [3]

  methyl groups could be added to tumour suppressor gene

  transcription of tumour suppressor gene is inhibited

  leading to uncontrolled cell division