M2:T8: attachment

• glycocalyx 


  layer of viscous material surrounding bacteria as both a capsule and slime layer

  • important as it allows bacterial cells to adhere to surface
• advantages of biofilms

  aggregates of cells and polymer matrix attached to surface

  • complex interactions
  • advnatges

  1. pathogenic bac adhering to tissue
  2. proetct against dehydration and loss of nutrients and phagocytes
• fibrae 


  surface appendages of gram -ve bac

  • adhesion fusion
  • short and layer in numbers
• where are biofilms found

  1. Solid substrate with moisture
  2. soft tissue
• common infections vs environmental issues of biofilms 


  commone infections: CF, ear infection, legionaries, UTI, oral and implants

  environmental: clogs drains, ships and food industry