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2nd Year: 2nd Sem
AUBF Lec
Amniotic Fluid
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2nd Year: 2nd Sem > AUBF Lec > Amniotic Fluid
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Specimen Collection and Handling
2nd Year: 2nd Sem > AUBF Lec > Amniotic Fluid
15 cards
Cards (65)
Where is amniotic fluid produced?
placenta
Amniotic fluid surrounds the what during what?
Fetus
during
gestation
Amniotic fluid can be found inside the what?
amniotic sac
Amniotic fluid provides a protective what?
cushion
Amniotic fluid allows for fetal what?
movement
Amniotic fluid stabilizes what?
temperature
Amniotic fluid permits what?
proper lung development
What trimester of pregnancy are genders and genetic disorders detectable?
2nd
trimester
Amniotic fluid testing is done for the antenatal diagnosis of what?
genetic
and
congenital
disorders
Amniotic fluid assesses what?
fetal lung maturity
Amniotic fluid testing assessing the degree of what?
fetal distress
What are the 3 composition of amniotic fluid?
Fetal urine
,
lung fluid
, and
fetal swallowing
During the 1st trimester, the composition of the amniotic fluid is similar to what? and with what?
maternal plasma
with
sloughed off fetal cells
During the 2nd trimester, the major contributor to the amniotic fluid is what?
fetal urine
During the 2nd trimester, what regulates the increase in volume caused by fetal urine production?
fetal swallowing
When fetal urine production begins, what components increases?
Creatinine
,
urea
, and
uric acid
When fetal urine production begins, what components decreases?
glucose
and
protein
What analyte is used to determine the FETAL AGE?
Creatinine
What analytes are used to differentiate MATERNAL URINE from AMNIOTIC FLUID?
Creatinine
,
Urea
,
Glucose
, and
protein
What analytes are HIGHER IN AMNIOTIC FLUID than in maternal urine?
Glucose
and
Protein
What test is performed to differentiate AMNIOTIC FLUID from other body fluids?
Fern test
Before 36 WEEKS of gestation, what is the normal amount of creatinine in the amniotic sac?
1.5mg/dL
to
2mg/dL
A fetal age of MORE THAN 36 WEEKS should contain how much creatinine in the amniotic fluid?
greater
than
2mg/dL
What is the amount of UREA in maternal urine?
300mg/dL
What is the amount of UREA in amniotic fluid?
less than 30mg/dL
What is the amount of CREATININE in maternal urine?
10mg/dL
What is the amount of CREATININE in AMNIOTIC FLUID?
less than 3.5mg/dL
What analytes may or may not be present during pregnancy, making them an unreliable indicators?
glucose
and
proteins
What amniotic fluid test requires a REFRIGERATED or FROZEN specimen?
Fecal lung maturity test
Maternal urine vs. amniotic fluid tests are done to determine possible rupture in where?
amniotic sac
Maternal urine vs. amniotic fluid tests are done to determine accidental puncture of the what during amniocentesis?
maternal bladder
What is a positive result of the Fern Test indicating the sample is an amniotic fluid?
fern-like crystals
Positive fern test is also indicative of the presence of what?
sodium chloride
and
protein
What is the peak volume of amniotic fluid?
800-1200
ml
Polyhydramnios
: Abnormally large volume of amniotic fluid during pregnancy (<1200mL)
Polyhydramnios can be due to the absence/decreased of
FETAL SWALLOWING
or
NEUTRAL
TUBE DISORDERS
Oligohydramnios
: decreased amniotic fluid volume (<800mL)
Oligohydramnios can be caused by increased
FETAL SWALLOWING
,
URINARY TRACT
deformities, and membrane
LEAKAGE
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