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Biochem
Biochem: Lipids
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Larina Dela Peña
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Lipid Metabolism
Biochem > Biochem: Lipids
34 cards
Cards (59)
a class of biological molecules defined by low solubility in water and high solubility in non-polar solvents
lipids
lipids may be ___ or ___ (possess both polar and non-polar groups)
hydrophobic
,
amphipathic
lipids have ___ attraction between other lipids molecules
London dispersion
For Lipids, lesser surface area of contact of one molecule to another will result to ___
lower IMFA
carbon bonds makes saturated fatty acids ___ molecules
extremely flexible
Unsaturated fatty acids have ___ melting points than saturated ones
lower
essential FAs: linoleic (___) and linolenic (___) acids
Omega-6
,
Omega-3
Short-chain fatty acids have ___, whereas long-chain fatty acids are ___
some
solubility
,
insoluble
Found in adipocytes, major energy reserve and the principal neutral derivatives of glycerol found in animals
Triacylglycerols
Triglycerides rich in unsaturated fatty acids are generally liquid at room temperature and are called ___
oils
Triglycerides rich in saturated fatty acids are generally semisolids or solids at room temperature and are called ___
fats
What hydrolyzes TAGs to become DAGs and MAGs?
lipase
Addition of hydrogen across C–C multiple bonds, which increases degree of saturation
Hydrogenation
Leads to C=C breakage that produces both aldehyde and carboxylic acid products
Oxidation
Odor released due to oxidation
rancid
Phospholipids contain: ___, ___, and ___
one or more
fatty acids
, a
phosphate
group, and an
alcohol
Differences of glycerophospholipids to TAGs:
function as components of cell membranes
polar
If the other alcohol is choline, the glycerophospholipid is called a ___
phosphatidylcholine
(
lecithin
)
linkage between sphingosine and FA
amide
linkage between sphingosine and monosaccharide or oligosaccharide
glycosidic
linkage
Simplest sphingoglycolipids; Occur primarily in brain (7% of dry mass)
Cerebrosides
Complex sphingoglycolipids; Occur in the gray matter of the brain and in the myelin sheath
Gangliosides
Such is the case for ganglioside GM2 in the brains of ___ victims.
Tay-Sachs disease
Arachidonic acid (20:4) derivatives; hormone-like molecules; have a very short “life”
Eicosanoids
Three hormones produced by arachidonic acid (eicosanoids):
prostaglandins
, thromboxane,
leukotrienes
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