HISTOLABBBBB TABLES

• Monocyte

  Major Location : Blood
• Monocyte Main Function :

  Precursor of macrophages
• Macrophage

  Major Location : CT, lymphoid organs, Lungs, BM, Pleural & Peritoneal cavities
• Kupffer Cell

  Major Location: Liver (Perisinusoidal)
• Microglial Cell

  Major Location : CNS
• Macrophage, Kupffer, Microglial Cell Main Function :

  Produces cytokines, chemotactic factors, and other substances participating in inflammation, antigen processing, and presentation
• Langerhans Cell

  Major Location : Epidermis
• Dendritic Cell

  Major Location : Lymph nodes, Spleen
• Langerhans, Dendritic Cell Main Function : Antigen processing and presentation
• Osteoclast

  Major Location : Bone
• Osteoclast Main Function : Localized digestion of bone matrix
• Multinuclear Giant Cell

  Major Location : In CT under pathologic

  conditions
• Multinuclear Giant Cell Main Function :

  Segregation and digestion of foreign

  bodies
• Fibroblasts (fibrocytes)


  extracellular fibers and ground substance
• Plasma cells


  antibodies
• Lymphocytes (several types)


  various immune/defense functions
• Eosinophilic leukocytes


  Modulate allergic/vasoactive reactions and defense against parasites
• Macrophages


  phagocytosis of ECM components and debris, antigen processing and presentation to immune cells, and secretion of growth factors, cytokines, and other agents
• Mast cells and basophilic leukocytes


  pharmacologically active molecules (e.g., histamine)
• Adipocytes


  neutral fats
• Neutrophilic leukocytes


  Phagocytosis of bacteria
• Type I


  Skin, tendon, bone, dentin
• Type I


  Tension
• Type II


  Cartilage, vitreous body
• Type II


  Pressure
• Type III 


  Maintenance
• Type V


  Fetal tissue, placenta skin, bone, interstitial tissues
• Type XI


  Cartilage
• Type V, XI


  Participates in Type II collagen function
• Type IV


  Basal lamina, external lamina
• Type IV


  Filtration & support if epithelial cells
• Type X


  Hypertrophic cartilage in endochondral ossification
• Type X


  Increases matrix density
• Type VII


  Epithelial basement membrane
• Type VII


  Anchor basal lamina to reticular lamina
• Type IX


  Cartilage, vitreous body
• Type IX


  Bind proteoglycans; associated with type II
• Type XII


  Placenta, skin, tendons
• Type XII


  Interact with type I
• Type XIV


  Placenta, bone