3.3.11.3 nucleophilic properties

• nucleophilic substitution

  • amines can act as nucleophiles because the lone electron pair is attracted to d+ regions on other molecules
  • amines can substitute halides on halogenoalkanes to form primary, secondary or tertiary amines and quaternary ammonium salts
• nucleophilic addition-elimination 


  amines can undergo this with acyl chlorides to produce amides and N-substituted amides
• nucleophilic addition-elimination mechanism

  
• the same nucleophilic addition-elimination mechanism can also occur with acid anhydrides to produce an amide and a carboxylic acid
• N-substituted amides