Glycogen metabolism

    Cards (7)

    • Glycogen
      A branched polymer of glucose
    • Glycogen
      • Main chain has alpha 1,4 linkages
      • Side chain has alpha 1,6 linkages
      • Has a helical structure
      • Has a branch occurring every 8-12 glucoses
    • Glycogen chain
      12-14 glucose residues
    • There are up to 120,000 glucose per glycogen
    • Glycogen granules make up to 10% of liver mass and 1-2% of muscle
    • Phosphorylase active site
      Contains a Pyridoxal phosphate (PLP) prosthetic group
    • Phosphorylase cannot break 1,6 bonds or 1,4 bonds (within 4 units of branch point)
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