DOSE/SIDE EFFECTS

• What is the dose of GTN?

  • Myocardial ischaemia = 0.4mg/5min. If cautioned, every 10min
  • STEMI = 0.4mg with caution
  • CPO = 0.8mg/5min. If cautioned, every 10min
  • control of HTN = 0.4mg/5min

  ONSET:

  • 1-2min

  DURATION:

  • 15-30min

  ADVERSE EFFECTS:

  • HoTN
  • tachycardia
  • headache
  • lightheadedness
• What is the dose of IPRATROPIUM?

  • 0.5mg for adults + children
  • administer ONCE only
  • neb undiluted with 5mg of salbutamol

  ONSET:

  • 2-5min

  DURATION:

  • 6hr

  ADVERSE EFFECTS:

  • tachycardia
  • dry mouth
  • blurred vision
• What is the dose of PREDNISONE/PREDNISOLONEE?

  • 40mg for adult
  • see paediatric table (inline with weight e.g. 30kg = 30mg)
  • administered PO
  • over 10yr = prednisone tab
  • under 10yr = prednisolone syrup

  ONSET:

  • 30-60min

  DURATION:

  • 24hr

  ADVERSE EFFECTS:

  • fatigue
  • GI reflux
  • Na and water retention
• What is the dose for SALBUTAMOL?

  • MDI = one puff, followed by 6 breaths. Repeat 6 times
  • Neb for bronchospasm = 5mg for adult + child. Repeat as required. Initial dose combined with 0.5mg of ipratropium.
  • Neb undiluted using medical air for COPD. Oxygen for other indications

  ONSET:

  • 2-5min

  DURATION:

  • 1-2hr

  ADVERSE EFFECTS:

  • tremor
  • tachycardia
• What is the dose/administration for ADRENALINE?

  • topical = dilute each mg to a total of 10ml using 0.9% NaCl. The solution is 1:10,000 and contains 0.1mg/ml
  • IN: dilute each mg to a total of 10ml using 0.9% NaCl. The solution is 1:10,000 and contains 0.1mg/ml
  • Neb for stridor = 5mg undiluted
  • IM = 0.5mg undiluted.

  ONSET:

  • IV = 5-10sec
  • IM = 2-5min
  • Neb, IN, topical = on contact

  DURATION:

  • cardiovascular = 5-15min
  • mast cell = several hr

  ADVERSE EFFECTS:

  • tachycardia + tachydysrthymia
  • myocardial ischaemia
  • hyperglycaemia
  • ventricular ectopy
  • HTN
  • nausea + vomit
  • tremor, anxiety, sweat
• What is the dose of ASPIRIN?

  300mg chewed

  ONSET:

  • 30-60min

  DURATION:

  • anti-platelet = 3-5 days

  ADVERSE EFFECTS:

  • increased bleeding
  • GI issues (long term use)
• What is the dose/administration of ONDANSETRON?

  • 4mg IM for adult
  • child = see drug tables
  • IM can be repeated ONCE after 20min if needed

  ONSET:

  • IV = 2-5 min
  • IM = 5-10min

  DURATION:

  • 4-8 hr

  ADVERSE EFFECTS:

  • headache
  • flushing
• Dose/administration for GLUCAGON:

  • 1mg IM once for adult or child >5yr
  • 0.5mg IM once for <5yr

  ONSET:

  • 5-10min

  DURATION:

  • 15-60min
• What is the dose/administration for GLUCOSE GEL?

  • 10-20g for all ages
  • administer one sachet and repeat every 10min if no improvement
  • administer PO

  ONSET:

  • 5-10min

  DURATION:

  • 30-60min

  INTERACTIONS:

  • none
• What is the dose of LORATADINE?

  • 10mg for >12
  • 5mg for <12
  • administered PO

  ONSET:

  • 30-60min

  DURATION:

  • 12-24hr

  INTERACTIONS:

  • none
• What is the dose for O2?

  • nasals: 1-4L/min
  • acute mask: 6L/min
  • neb: 8L/min
  • non-rebreather: 10L/min
  • BVM: 10L/min